Microfluidic chips, the next rev...

In recent years, microfluidics has developed rapidly with the development of technology. Microfluidics is the science and technology of microscale (tens to hundreds of microns) integrated channel systems. Trace amounts of liquid (typically 10-9 to 10-18 liters) flow under the control of the system by a specific model. The development of such a high-tech microfluidics has actually been heard for decades, and the requirement of microvolume and planarization for biochemical analysis was a good driving force for the development of microfluidics. Since then, the concept of "wafer labs" and microscale integrated analysis systems (μTAS) has been gradually established.

In microfluidic fields, the specific surface area increases as the size of the fluid decreases, showing characteristics different from those of macroscopic fluids. In this paper, three main characteristics of microfluidics are considered: high efficiency of mass heat transfer, relative advantage of viscosity over inertial forces, and significant surface effects. In addition, the highly integrated microfluidic system also promotes the coexistence of multiple fluid phases and multiple interactions. Such properties make it possible to control and manipulate single fluids and fluid interfaces using microdevices, allowing microfluidics to be used in a wide range of applications in physics, chemistry, biology, medicine, and engineering.

Bonding and lamination of microfluidic chips

Today, I would like to discuss with you the revolutionary impact of microfluidics on biochemistry. The application of microfluidics in biochemistry can be very wide, which involves enzyme analysis, DNA analysis (such as polymerase chain reaction and high-throughput sequencing), proteomics analysis, etc. The basic idea of microfluidic biochip is to integrate assay operations, sample processing and sample preparation into a single chip, which gives it high-throughput characteristics. The chip can also play an important role in clinical pathology, especially in the direct diagnosis of diseases. In addition, microfluidic-based devices, such as those that can continuously sample air or water samples, and real-time detection devices can be used to detect biochemical toxins and pathogenic microorganisms. In addition to the above-mentioned assays, microfluidics has become a powerful tool for biologists to study and control the cellular environment, and a "godsend" for new discoveries in cell growth, aging, etc. Next, we will look at some specific examples of how microfluidics performs its role.

In terms of bioanalysis, microfluidics shines in ions, small molecules, and biomolecules such as nucleic acids and proteins, which have led to a revolution in many standard biomolecular techniques. It is a platform for technologies such as multiplex enzyme chain reaction (PCR), reverse transcription PCR (RT-PCR), and enzyme-linked immunosorbent assay (ELISA). In addition, droplet microfluidics, a microfluid, has been able to be successfully analyzed at the cellular level, and many classical cellular manipulations can be done in microdroplets.

Previously, when talking about chemical reactions, the jars and bottles that could not be cleaned by any brush were the ones that came to mind. But today, microfluidic droplets can exist as a small chemical reactor, and researchers can achieve precise control over their environment. It is used in a wide variety of reactions, including titration, precipitation, hydrolysis, etc. A good example is the droplet microfluidic platform for the anticoagulant argatroban. Using this technology, researchers can determine the appropriate dose of argatroban by measuring clotting time with partial thrombospondin kinase activation time on a single wafer. In addition to the aqueous phase reaction, microdroplets also support the organic phase reaction. However, at this time, the materials used to make the instrument must be carefully selected to avoid deformation of the tube due to corrosion by organic solvents. Sulfur hydroxyl polymers are a good choice and have a better organic stability compared to PDMS materials.

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New microfluidic device improves...

A new microfluidic device allows scientific researchers to create alternating electric fields in a three-dimensional natural environment.

Malaysian researchers have designed a three-dimensional microfluidic shaping service platform to test the therapeutic effects of cancer treatment electric fields, a new form of cancer treatment based on the alternating electric fields that have been approved by the FDA for the treatment of malignant gliomas, reports McMasters.

The 3D microfluidic device was developed and designed by an elite team of scientists from the Malaysia-MIT Science Research and Technology Consortium, who created an alternating electric field in a 3D natural environment that is more physiologically appropriate than the standard 3D cell culture media service platform.

This research has shown that electric field therapy reduces the migration and spread of tumour cells. Excitingly, the growth and development rate of tumour cells treated with electric field therapy was reduced by 35% relative to tumour cells that were not treated with electric field therapy. For non-tumour cells, such as endothelial cells around the capillaries surrounding malignant tumours, there was no significant harm.

Microfluidics

"With this 3D microfluidic device, physicians will be able to specify the amount of electric field resistance necessary for each patient to be treated, enhancing their treatment outcome."

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Selection and use of disposable catering enterpr...

wooden fork

During the Spring Festival, family gatherings are essential. Some families are accustomed to buy disposable plastic lunch boxes before the Spring Festival, because relatives and friends, dishes and cups and plates such as dishes are not enough or to reduce the trouble of washing dishes. In this regard, the city consumer association organization work management personnel to recommend that the general public in the purchase and use of disposable catering products pay attention to the "five look".

According to the production of materials used, mainly PET (polyethylene terephthalate) PE (polyethylene), PP (polypropylene), and PS (polystyrene), four materials are non-toxic, odorless and tasteless. PE is generally not used for food packaging, PP can be heated in the microwave oven. Cycle mark 1-7 each speaks, logo 5 can be recycled. Consumers in the purchase and use of disposable plastic tableware products, be sure to pay attention to the following six points: 1, look at the logo. To see if there is a QS logo, production license number, manufacturer, production address and other information to improve product quality assurance. Should choose products with good packaging, pay attention to the production date and shelf life, try to choose products within the shelf life, in case there are bacteria, mold; look at the appearance. To buy smooth surface, uniform color disposable plastic catering utensils, try to choose no decorative pattern of colorless transparent products; look at the smell. 4, look at the smell: you can first smell there is no strange smell, odor, to prevent the use of food and food crosstalk, affecting food safety. Whether the product is too soft to pinch, try not to choose too soft to pinch the product.

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Most IT businesses have however

The ROI of SD-WANSoftware-defined broad area networking (SD-WAN) is usually a modern merchandise classification. Most IT businesses have however to create their initial buy, though many are undertaking technological investigations and including SD-WAN gateways into their infrastructure designs. On the other hand, the monetary arguments demanded for budgetary acceptance are still a pending action. Although there exists a common belief amid networking team that SD-WAN lessens expenses by shifting targeted visitors from expensive private WAN inbound links to broadband World-wide-web connections, quantifying this as well as other SD-WAN advantages demands a extra arduous strategy.

Software-Defined Wide Area Networking (SD WAN) is a transformational approach to simplify branch office networking and assure optimal application performance.

Quantifying the SD-WAN return on financial commitmentMaking an ROI calculation may be time intensive, so Business Administration Associates (EMA) has generated a paper that gives detailed calculations and explores supplemental quantitative and qualitative added benefits of SD-WAN. Their analysis concluded that, even though the operational and capital charge personal savings are substantial more than a 5-year time period, IT productivity gains and improved community uptime provided even higher payback around the investment. This text explores the broader list of ROI concerns to help you IT administrators create a economical case for SD-WAN investments.

Hazel Lee Sung yan

Decreased running expensesAt the core of SD-WAN operation is transforming community connections from personal MpLS backlinks to broadband Web. Secured by encrypted tunnels and built-in firewalls, broadband Online connections commonly price 95-to-99 per cent much less for each megabit-per-second than personal MpLS one-way links. Internet hyperlinks are a great deal of much less expensive that early adopters of SD-WAN significantly increase their bandwidth and they are however conserving network connectivity prices.The economic calculation employed by EMA for any 100-branch community assumes that every branch replaces two 1.5 Mbps MpLS backlinks with a single 1.five Mbps MpLS url and 25 Mbps of broadband Net. This configuration delivers a number of benefits. 1st, an practically 9x boost in bandwidth whilst however reducing in network connectivity prices by 20%. Second, every department can now instantly access cloud products and services without having having to transit a central gateway. Blended, these end in much better overall performance for cloud purposes and high-bandwidth solutions this sort of as video conferencing and prosperous media.Decreased funds expendituresMoney investments make up a smaller share of the network’s 5-year value, but you can find still savings to be had with SD-WAN. Digital appliances, cloud-based administration, and dynamic path choice all add into the savings. Decoupling the hardware in the services, much like digital servers and storage, gets rid of much in the expense and complexity of deploying physical routers.

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得體淡泊，學會寬容！

何為寬容？當一只腳踏在紫羅蘭花瓣上時，它卻將香味留在了那只腳上，這就是寬容！

 

得體淡泊，學會寬容！天空容留每一片雲彩，不論其美醜，故天空廣闊無比；

 

高山容留每一塊岩石，不論其大小，故高山雄偉壯觀；

 

大海容留每一多浪花，不論其清濁，故大海浩瀚無際。

 

寬容是人間的潤滑劑，有了寬容，人間就少了許多糾紛，多了一份寧靜；少了許多敵對，多了一些美好。有了寬容，人間才會變成美好的天堂。

 

有一副古聯這樣寫道：和為天下傳家寶，忍為人間化氣丹。意即只要人與人之間能和睦相處，就是普天下最寶貴的財富；遇事只要奉行一個忍字，再深的矛盾都可以化解。

 

記住別人的好，忘掉別人的壞，你就會在幸福而又寬容的天空下自由地翱翔！

 

上蒼給了我們同樣的生命，當走到人生的盡頭時，能夠留下的會是什麼呢？我們留給別人的又會是什麼呢？學會寬容別人，也是善待自己的一種方式。生活，是在寬容中越走越寬廣的。時間會沖淡痛苦，但我們為什麼要等時間來沖淡呢？學會及早的忘卻，及早的原諒，及早的享受生活，生命裏美麗的日子不是會多些嗎？

 

歲月的美，就在於它流逝後再也不會回來。能在有限的日子裏多些美好時光，就是在延長自己的生命！

 

學會寬容別人，在我們老的那一天，就會發現生命的每個端點都不再有因狹隘而造成的遺憾，也會給他人的生命增加快樂和亮點。畢竟，只有美，才是永恆的！

 

水至清則無魚，人至察則無友。一個人必須具有容納怨怒與恥辱的能力，再加上包容一切善惡賢愚的態度，才能夠寬容他人。

 

穿梭於茫茫人海中，面對一個小小的過失，常常一個淡淡的微笑，一句輕輕的歉語，帶來包涵諒解，這是寬容；在人的一生中，常常因一件小事、一句不注意的話，使人不理解或不被信任，但不要苛求任何人，以律人之心律已，以恕已之心恕人，這也是寬容。所謂"己所不欲，勿施於人”也寓理於此。

 

學會寬容，意味著您不再心存疑慮。

 

世界上最寬闊的是海洋，比海洋寬闊的是天空，比天空更寬闊的是人的胸懷。－雨果

 

相傳古代有位老禪師，一日晚在禪院裏散步，突見牆角邊有一張椅子，他一看便知有位出家人違犯寺規越牆出去遛達了。老禪師也不聲張，走到牆邊，移開椅子，就地而蹲。少頃，果真有一小和尚翻牆，黑暗中踩著老禪師的背脊跳進了院子。當他雙腳著地時，才發覺剛才踏的不是椅子，而是自己的師傅。小和尚頓時驚慌失措，張口結舌。但出乎小和尚意料的是師傅並沒有厲聲責備他，只是以平靜的語調說："夜深天涼，快去多穿一件衣服。”老禪師寬容了他的弟子。他知道，寬容是一種無聲的教育。

 

心理學家指出：適度的寬容，對於改善人際關係和身心健康都是有益的，這種寬容，指的是對於子女或別人在生活、工作、學習中的過失、過錯採取適當的"羞辱政策”，有效地防止事態擴大而加劇矛盾，避免產生嚴重後果。大量事實證明，不會寬容別人，亦會殃及自身。過於苛求別人或苛求自己的人，必定處於緊張的心理狀態之中。由於內心的矛盾衝突或情緒危機難於解脫，極易導致機體內分泌功能失調，諸如使兒茶酚胺類物質──腎上腺素、去甲腎上腺素過量分泌，引起體內一系列劣性生理化學改變，造成血壓升高，心跳加快，消化液分泌減少，胃腸功能紊亂等等，並可伴有頭昏腦脹、失眠多夢、乏力倦怠、食欲不振、心煩意亂等症候。緊張心理的刺激會影響內分泌功能，而內分泌功能的改變又會反過來增加人的緊張心理，形成惡性循環，貽害身心健康。有的過激者甚至失去理智而釀成禍端，造成嚴重後果。而一旦寬恕別人之後，心理上便會經過一次巨大的轉變和淨化過程，使人際關係出現新的轉機，諸多憂愁煩悶可得以避免或消除。

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