June 16, 2021

New microfluidic device improves...

A new microfluidic device allows scientific researchers to create alternating electric fields in a three-dimensional natural environment.

Malaysian researchers have designed a three-dimensional microfluidic shaping service platform to test the therapeutic effects of cancer treatment electric fields, a new form of cancer treatment based on the alternating electric fields that have been approved by the FDA for the treatment of malignant gliomas, reports McMasters.

The 3D microfluidic device was developed and designed by an elite team of scientists from the Malaysia-MIT Science Research and Technology Consortium, who created an alternating electric field in a 3D natural environment that is more physiologically appropriate than the standard 3D cell culture media service platform.

This research has shown that electric field therapy reduces the migration and spread of tumour cells. Excitingly, the growth and development rate of tumour cells treated with electric field therapy was reduced by 35% relative to tumour cells that were not treated with electric field therapy. For non-tumour cells, such as endothelial cells around the capillaries surrounding malignant tumours, there was no significant harm.


"With this 3D microfluidic device, physicians will be able to specify the amount of electric field resistance necessary for each patient to be treated, enhancing their treatment outcome."

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